个人简历

王浩，博士，2004年本科毕业于天津医科大学药学院，2009年硕士毕业于北京协和医学院药物化学专业，2012年博士毕业于北京协和医学院放射医学专业，2017-2020年哈佛大学医学院博士后。2021年加入天津大学医学工程与转化医学研究院，目前主要从事放射医学与生物医学工程，特别是分子影像，生物材料等方面研究。在Science Advances (1), Advanced Materials (1), Advanced Funcational Materials (2), Nano Letters (2), Nano Today (1), Trends in Pharmacological Sciences (1)，Coordination Chemistry Review (2),等期刊发表论文50余篇；多篇入选1‰的热点论文和ESI高被引论文，总引用次数超5000次；申请发明专利8项。主持完成国家自然科学基金1项，国家重点研发计划子课题1项，天津市自然科学基金面上项目2项。中国毒理学会放射毒理专业委员会委员。

主要研究方向

1.小分子药物及超小团簇分子的设计合成及其在放射医学、重大疾病治疗中的应用

2.红外二区荧光分子探针的合成及其活体示踪和三维可视化

3.新型植入脑机接口材料在重大神经系统疾病的诊断和治疗中的应用

代表性论文与著作：

1.Si Sun, Fangzhen Tian, Huanhuan Qiao, Qi Xin, Xinxu Zhang, Nan Song, Yuxing Yan, Ling Liu, Yili Wang, Lijie Zhang, Ke Chen, Jiang Yang, Shu Zhang, Jianning Zhang, Yonghui Li*, Hao Wang*, Xiao-Dong Zhang*, Metabolic Enzyme-Inspired Molecular Clusters for Advanced Type 2 Diabetic Complications by Alleviating Immunosuppression, Advanced Materials, 2026，利用机器学习方法设计团簇分子抑制剂。

论文链接：https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202518331

2.Haoyue Yan, Di Ma, Huizhen Ma, Jing Zhang, Xiao-Dong Zhang, Hao Wang*, Visualized diagnosis in the second near-infrared window, Coordination Chemistry Reviews, 2026.

3.Huizhen Ma, Xiaoning Zhang, Ling Liu, You Huang, Si Sun, Ke Chen, Qi Xin, Pengfei Liu, Yuxing Yan, Yili Wang, Yuan Li, Haile Liu, Ruoli Zhao, Kexin Tan, Xinzhu Chen, Xun Yuan, Yonghui Li, Ying Liu, Haitao Dai, Changlong Liu, Hao Wang*, & Xiao-Dong Zhang*, Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition, Science Advances, 2023，具有生物活性的红外二区团簇分子探针。

论文链接：https://www.science.org/doi/10.1126/sciadv.adh7828

Phys. Org专题报道，https://phys.org/news/2023-08-bioactive-near-infrared-ii-clusters-3d.html

4.Xinyu Sun, Shuangjie Liu, Yadong Zhe, Hao Wang*, Xiao-Dong Zhang*，Transducer Materials for Wireless Neuromodulation，Advanced Functional Materials, 2025.

5.Shasha Li, Qi Xin, Yuan Li, Huizhen Ma, Haoyue Yan, Siyu Ao, Hongwei Li, Qi Wang, Zhidong Wang*, Pengfei Liu*, Hao Wang*, Xiao-Dong Zhang*, Three-Dimensional Visualization of Breast Cancer Pathology Evolution in Clinical Patient Tissues with NIR-II Imaging, Nano Letters, 2024

6.Shasha Li, Kefeng Jia, Siyu Ao, Huizhen Ma, Jiayan Zang, Haoyue Yan, Qi Xin, Yuxing Yan, Di Ma, Yuxuan Huo, Shuyu Yang, Ling Liu, Shibo Li, Zili Zhang, Pengfei Liu*, Hao Wang*, Xiao-Dong Zhang*, Atomically Precise Au₃₂ Clusters for 3D Visualization of Pathological Progression in Sepsis-Induced Multi-Organ Injury, Nano Letters, 2025

7.Shasha Li, Kefeng Jia, Ling Liu, Haoyue Yan, Jiayan Zang, Siyu Ao, Qi Xin, Di Ma, Shibo Li, Shuyu Yang, Xiao-Dong Zhang, Zhidong Wang*, Huizhen Ma*, Pengfei Liu*, Hao Wang*， High-brightness, atomic precision gold clusters for three-dimensional visualized pathological monitoring，Chemical Engineering Journal，2025

8.Si Sun, Di Liu, Nan Song, Qi Xin, Lingxia Li, Sufei Zhou, Huanhuan Qiao, Lijie Zhang, Yuxing Yan, Yili Wang, Ke Chen, Fangzhen Tian, Jiang Yang, Hao Wang*, Xiao-Dong Zhang*，Single active Au₁O₅ clusters for metabolism-inspired sepsis management through immune regulation，Nano Today, 2024

9.You Huang, Ke Chen, Ling Liu, Huizhen Ma, Xiaoning Zhang, Kexin Tan, Yuan Li, Ying Liu, Changlong Liu, Hao Wang*, Xiao-Dong Zhang，Single Atom-Engineered NIR-II Gold Clusters with Ultrahigh Brightness and Stability for Acute Kidney Injury，Small，2023.

10.Hao Wang, Xiaoyu Mu, Hua He, Xiao-Dong Zhang*. Cancer radiosensitizers. Trends in Pharmacological Sciences. 2018, 39 (1): 24-48. ESI高被引，热点论文，引用664次。