副教授

王玲
职称:副教授
办公室:天津大学医工院办公楼106室
邮箱:lwang2015@tju.edu.cn
个人简介
王玲,副教授/高级工程师,长期聚焦于认知、运动等脑功能障碍(社交障碍、脑卒中、帕金森病等)的病理机制和新型神经调控技术(聚焦超声刺激、经颅磁刺激等)研究。主持国家自然科学基金、中国博士后面上基金、国家重点研发计划(子课题)等项目,作为技术骨干参与2030“脑科学与类脑研究”重大专项、临港实验室-中国航天员中心人因工程国家级重点实验室“求索太空脑计划”项目等。以第一或通讯作者在神经科学、神经工程领域重要期刊发表学术论文近20篇,授权国家发明专利2项,多次受邀参加IEEE EMBC、ICBBE等国际会议并作报告。
主要研究方向
新型神经调控技术及其在神经系统疾病的应用
主要技术:聚焦超声刺激、经颅磁刺激、光遗传学、在体钙成像技术等
代表性学术成果
[1] Ling Wang#, Sutong Wang#, Weiyi Mo, Yaqing Li, Qing Yang, Yutao Tian, Chenguang Zheng, Jiajia Yang*, Dong Ming*. Ultrasound stimulation attenuates CRS-induced depressive behavior by modulating dopamine release in the prefrontal cortex, IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2024, 32: 1314-1323.
[2] Rong Liang#, Ling Wang#, Xinyao Li, Xiaohui Liu, Haonan Chang, Qing Xu, Yue Wang, Dong Xu, Dong Liu, Jiajia Yang*, Chenguang Zheng*, Dong Ming*. Repetitive transcranial magnetic stimulation rescues simulated space complex environment-induced emotional and social impairments by enhancing neuronal excitability in the medial prefrontal cortex, Cerebral Cortex, 2023, 33(11): 7148-7162.
[3] Ling Wang#, Jiajia Yang#, Xi Xiao, Chenguang Zheng, Dong Ming*. VEGF modulates the neural dynamics of hippocampal subregions in chronic global cerebral ischemia rats. Neuromolecular Medicine, 2021, 23(3): 416-427.
[4] Yimeng Wang#, Yang Bai#, Xi Xiao, Ling Wang, Ganjiang Wei, Mingkun Guo, Xizi Song, Yutao Tian, Dong Ming, Jiajia Yang*, Chenguang Zheng*. Low-intensity focused ultrasound stimulation reverses social avoidance behavior in mice experiencing social defeat stress, Cerebral Cortex, 2022, 32(24): 5580-5596.
[5] Ling Wang, Faqi Wang, Shuang Liu, Xuening Yang, Jiajia Yang*, Dong Ming*. VEGF attenuates 2-VO induced cognitive impairment and neuronal injury associated with the activation of PI3K/Akt and Notch1 pathway. Experimental Gerontology, 2018, 102: 93-100.
[6] Ling Wang, Jingyu Wang, Faqi Wang, Chunhua Liu, Xuening Yang, Jiajia Yang*, Dong Ming*. VEGF-mediated cognitive and synaptic improvement in chronic cerebral hypoperfusion rats involves autophagy process. Neuromolecular Medicine, 2017, 19(2-3): 423-435.
[7] 魏赣#,王玲#,朱菁楠,王笑,臧禹然,郑晨光,杨佳佳* 明东. 综述前额叶皮层在社交行为中的作用,生物化学与生物物理进展,2024,51 (1): 82-93
[8] 张安琪#,王玲#,王宁,杨佳佳,郑晨光*,明东. 神经调控技术在阿尔茨海默病认知障碍研究中的应用. 生物化学与生物物理进展,2023,50 (10): 2276-2286
[9] 王玲,杨佳佳*,王发颀,万柏坤,明东*. 经颅磁刺激对抑郁模型动物的作用研究进展. 中国生物医学工程学报, 2018, 37(4): 498-507.
[10] Ganjiang Wei#, Ling Wang#, Jingnan Zhu, Xiao Wang, Yuran Zang, Jiajia Yang*, Chenguang Zheng*. Astrocytic TRPA1 as a target in reversing social avoidance by low-intensity focused ultrasound stimulation in mice. 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2024.
[11] Ning Wang#, Anqi Zhang#, Jiajia Yang, Ling Wang*, Chenguang Zheng*. The Pattern of CA1 c-Fos Expressing Place Cells Correlates with Learning Progression. 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2024.
[12] Zhaodi Liu, Yimeng Wang, Jiajia Yang, Ling Wang*, Chenguang Zheng*. Stable firing pattern of excitatory neurons in the prefrontal cortex of rats during social behaviors. 9th International Conference on Biomedical and Bioinformatics Engineering, 2022.
[13] Ling Wang#, Jiajia Yang#, Xi Xiao, Chenguang Zheng, Dong Ming*. Modulation of repetitive transcranial magnetic stimulation on mood and cognitive function in simulated weightlessness rats. 7th International Conference on Biomedical and Bioinformatics Engineering, 2020.
[14] Ling Wang#, Jiajia Yang#*, Faqi Wang, Peng Zhou, Kun Wang, Dong Ming*. Modulation of low-frequency pulsed magnetic field on hippocampal neural oscillation in depression rats. 40th International Conference of the IEEE Engineering in Medicine and Biology Society, 2018.
科研项目
[1] 2023.01-2025.12,国家自然科学基金青年科学基金项目, 低强度聚焦超声调节前额叶神经活动改善小鼠社交障碍的作用与机制研究,项目负责人
[2] 2023.11-2026.10,国家重点研发计划, 基于微弱物理场激励的细胞快速响应通讯元件精准构建技术, 子课题负责人
[3] 2022.09-2024.08,中国博士后科学基金面上项目, 低强度聚焦超声调节前额叶神经活动对社交回避行为的改善作用机制研究,项目负责人
[4] 2022.08-2027.07,科技创新2030“脑科学与类脑研究”重大项目,认知地图的神经机制,参与人
[5] 2024.01-2028.12,国家自然科学基金重点项目,脑机交互卒中运动康复系统及其诱导神经通路可塑恢复机制研究,参与人
[6] 2019.01-2022.12,国家自然科学基金面上项目,经颅磁刺激调控VEGF/PI3K/Akt通路改善模拟航天特因环境所致认知障碍的机制研究,参与人
获奖情况
国家级教学成果二等奖(2023)
第二届全国博士后创新创业大赛银奖(2023)
天津市教学成果奖特等奖(2022)
天津大学2024届本科生毕业设计(论文)优秀指导教师(2024)
上海神经科学学会神经调控分会年会二等奖(2024)
天津市生物医学工程学会青年论坛优秀论文一等奖(2022)