个人简介

张少芳，博士，天津大学助理研究员，博士毕业于天津大学，师从张晓东教授。研究方向为纳米医学，主要研究工作集中在生物纳米材料的构建、生物催化活性研究及其在脑创伤、神经修复以及伤口愈合等生物医学中的应用。近年在Nature Communications、Advanced Energy Materials、Theranostics、Advanced Materials、Nano Research、ACS Applied Materials & Interfaces、Chemistry of Materials等TOP期刊发表论文20余篇，1篇论文入选ESI高被引，申请国家发明专利2项，授权1项。主持国家自然科学青年基金1项、中国博士后面上项目1项、天津大学自主创新基金1项，合作主持天津市自然科学基金面上项目2项，参与国家重点研发计划、国自然面上项目等3项。获2023年国家资助博士后研究人员计划B档资助。获2024年第九届未来女科学家计划天津市候选人。

代表性学术成果

1）Shaofang Zhang^#, Yonghui Li^#, Si Sun^#, Ling Liu, Xiaoyu Mu, Shuhu Liu, Menglu Jiao, Xinzhu Chen, Ke Chen, Huizhen Ma, Tuo Li, Xiaoyu Liu, Hao Wang, Jianning Zhang, Jiang Yang, Xiao-Dong Zhang*. Single-atom Nanozymes Catalytically Surpassing Naturally Occurring Enzymes as Sustained Stitching for Brain Trauma. Nature Communications, 2022, 13: 4744. (ESI高被引, IF:17.8)

2）Shaofang Zhang^#, Ying Liu^#, Si Sun^#, Junying Wang, Qifeng Li, Ruijuan Yan, Yalong Gao, Haile Liu, Shuangjie Liu, Wenting Hao, Haitao Dai, Changlong Liu, Yuanming Sun, Wei Long, Xiaoyu Mu, Xiao-Dong Zhang*. Catalytic Patch with Redox Cr/CeO₂ Nanozyme of Noninvasive Intervention for Brain Trauma. Theranostics, 2021, 11: 2806-2821. (IF:12.4)

3）Kuo Wei, Zhiping Liu, Guangyuan Feng*, Yuanzhe Wang*, Shaofang Zhang*, Xiaojuan Li, Miao Zhang, Heen Li, Junshuang Zhou, Shengbin Lei*, Faming Gao*. Molecular Nanojunction Catalyst for Oxygen Evolution Reaction. Advanced Energy Materials, 2025, 2405366. (IF:24.4)

4）Shuangjie Liu, Yang Wang, Yue Zhao, Ling Liu, Si Sun, Shaofang Zhang, Haile Liu, Shuhu Liu, Yonghui Li, Fan Yang, Menglu Jiao, Xinyu Sun, Yuqin Zhang, Renpeng Liu, Xiaoyu Mu, Hao Wang, Shu Zhang, Jiang Yang, Xi Xie, Xiaojie Duan, Jianning Zhang, Guosong Hong, Xiao-Dong Zhang*, Dong Ming*. A Nanozyme-Based Electrode for High-Performance Neural Recording. Advanced Materials, 2023, 2304297. (IF:29.4)

5）Shaofang Zhang, Haiyan Ruan, Qi Xin, Xiaoyu Mu,* Hao Wang,* Xiao-Dong Zhang*, Modulation of the biocatalytic activity and selectivity of CeO₂ nanozymes via atomic doping engineering. Nanoscale, 2023, 15, 4408-4419. (IF:8.2)

6）Ling Liu^#, Shaofang Zhang^#, Guo Li, Yadong Zhe, Jiamin Liu, Xinxu Zhang, Jiahao Wei, Xin Sun, Yonghui Li, Xiao-Dong Zhang*; d-band Center Coordination Modulated Enzyme-like Activity in Fe-Cu Dual-Metal Single-Atom Nanozymes, Nano Research, 2024, 17, 5872-5883. (IF: 9.9)

7）Qi Xin, Shaofang Zhang^#, Si Sun, Nan Song, Yadong Zhe, Fangzhen Tian, Shu Zhang, Meili Guo, Xiaodong Zhang, Jianning Zhang*, Hao Wang*, Ruiping Zhang*, Multienzyme Active Nanozyme for Efficient Sepsis Therapy through Modulating Immune and Inflammation Inhibition. ACS Applied Materials & Interfaces, 2024, 16(28):36047-36062.

8）Ling Liu^#, Shaofang Zhang^#, Xinzhu Chen, Guo Li, Yonghui Li, Xiao-Dong Zhang*; Spin Cooperated Catalytic Activities in MnN4 based Single-atom Nanozyme: Mechanisms and a Brief Charge-spin Machine Learning Model, Chemistry of Materials, 2024, 36(6):2971-2984. (IF: 8.6)

9）Shaofang Zhang, Xiao-Dong Zhang*, Recent Advances in the Bioactive Structure and Application of Single-atom Nanozymes. Nano Biomedicine and Engineering, 2024, 16(1): 1-27

10）Haiyan Ruan^#, Shaofang Zhang^#, Hongguang Wang, Jiahui Pei, Ruoli Zhao, Xiaoyu Mu, Hao Wang*, Xiao-Dong Zhang*. Single-Atom Pd/CeO₂ Nanostructures for Mimicking Multienzyme. ACS Applied Nano Materials, 2022, 5(5): 6564-6574.

11）Qi Xin, Li Wang, Haiyan Ruan, Ling Liu, Si Sun, Jing Zhang, Menglin Wu, Xiaoyu Mu, Hao Wang, Shaofang Zhang*, Xiao-Dong Zhang. Multienzyme-Mimetic Activity of Gold/Cerium Oxide Nanozyme. Partical & Partical Systems Characterization, 2023, 40, 2200203.

12）Menglu Jiao, Xiao yu Mu, Si Sun, Hai yu Yang, Lufei Ouyang, Shaofang Zhang, Jiao Guo, Jian Meng, Ya Li, Huizhen Ma, Hao Wang, Jiahui Pei, Ruoli Zhao, Tianyu Liu, Wei Long, Xiao-Dong Zhang*, Ruiping Zhang. Establishing Bilateral Modulation of Radiation Induced Redox Damage via Biocatalytic Single Atom Engineering at Au Clusters. Chemical Engineering Journal, 2022, 445:136793. (IF:15.1)

13）Ruijuan Yan, Si Sun, Jiang Yang, Wei Long, Junying Wang, Xiaoyu Mu, Qifeng Li, Wenting Hao, Shaofang Zhang, Haile Liu, Yalong Gao, Lufei Ouyang, Junchi Chen, Shuangjie Liu, Xiao-Dong Zhang*, Dong Ming. Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma. ACS Nano, 2019, 13(10): 11552-11560. (IF:17.1)

专利

1)     单原子纳米酶及其制备方法（202210835421.0）

2)     单原子纳米酶缝合线的制备及其应用（202210818225.2）

科研项目

1) 国家自然科学基金青年基金，82302361，生物医学工程，2024-01至2026-12，30万元，在研，主持

2) 中国博士后面上项目，2023M732601，生物医学工程，2023-05至2025-12，8万元，在研，主持

3) 天津市自然科学基金，面上项目，生物医学工程，2023-10至2025-09，10万元，在研，合作主持

4) 天津市自然科学基金，面上项目，生物医学工程，2024-10至2026-09，10万元，在研，合作主持

5) 天津大学自主创新基金，2023XJC-0010，生物医学工程，2023-01至2023-12，5万元，结项，主持

获奖情况

1)     获2023年 国家资助博士后研究人员计划B档资助

2)     获2023年 天津大学优秀博士学位论文